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Adult acetaminophen dosage chart

Acetaminophen is a common pain reliever that comes in different strengths with different dosages and directions. Download and save this chart to help ensure you’re always taking the right dosages of acetaminophen products (for example, Tylenol® dosages).

Acetaminophen
ACETAMINOPHEN REGULAR STRENGTH for example Tylenol® Regular Strength 325 mg per pill
DOSE &
FREQUENCY
2 pills every 4 to 6 hours while symptoms last
DAILY LIMIT Do not take more than 10 pills in 24 hours, unless directed by a doctor
ACETAMINOPHEN EXTRA STRENGTH for example Tylenol® Extra Strength 500 mg per pill
DOSE &
FREQUENCY
2 pills every 6 hours while symptoms last
DAILY LIMIT Do not take more than 6 pills in 24 hours, unless directed by a doctor
ACETAMINOPHEN EXTENDED RELEASE for example Tylenol® 8HR Arthritis Pain 650 mg per pill
DOSE &
FREQUENCY
2 pills every 8 hours
DAILY LIMIT Do not take more than 6 pills in 24 hours
Acetaminophen dosage daily limit is 4,000 mg

Get your pain reliever dose right to avoid taking too much

Here’s what you can do to take acetaminophen safely:

One acetaminophen at a time icon

Take ONLY 1 medicine that contains acetaminophen at a time. Why?

More than 500 OTC and prescription medicines (see examples) contain acetaminophen. Taking more than one medicine that contains acetaminophen at a time increases your chance of taking too much and that can harm your liver.

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Don’t take more than 4,000 mg in 24 hours. Why?

4,000 mg is the acetaminophen dosage daily limit. Taking more increases your chance of harming your liver. For your safety, do not take more than 4,000 mg in 24 hours.

Dosing directions icon

Follow dosing directions. Why?

It is important to follow the directed dose and wait the correct amount of time between doses to avoid harmful side effects.

Remember: It is important to always read and follow the label. If you have any questions or are unsure which pain reliever may be right for you, talk with your healthcare professional.