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Adult NSAID dosage chart

NSAIDs, or nonsteroidal anti-inflammatory drugs, are a common type of pain reliever. Over-the-counter (OTC) NSAIDs include ibuprofen, naproxen sodium,and aspirin. They each have different dosages, directions, and daily limits. Download and save this chart for the correct OTC ibuprofen dosage, naproxen sodium dosage, and aspirin dosages to help ensure you are taking these pain relievers safely.

NSAIDs
IBUPROFEN for example Motrin® IB and Advil® 200 mg per pill
DOSE &
FREQUENCY
1 pills every 4 to 6 hours while symptoms last (if pain or fever does not respond to 1 pill, 2 pills may be used)
DAILY LIMIT Do not take more than 10 pills in 24 hours, unless directed by a doctor
Ibuprofen dosage daily limit is 1,200 mg
NAPROXEN SODIUM for example Aleve® 220 mg per pill
DOSE &
FREQUENCY
1 pill every 8 to 12 hours while symptoms last (for the first dose, you may take 2 pills within the first hour)
DAILY LIMIT Do not take more than 2 pills in any 8 to 12 hour period. Do not take more than 3 pills in 24 hours
Naproxen sodium dosage daily limit is 660 mg
ASPIRIN REGULAR STRENGTH for example Bayer® Regular Strength 325 mg per pill
DOSE &
FREQUENCY
1 or 2 pills every 4 hours, or 3 pills every 6 hours
DAILY LIMIT Do not take more than 12 pills in 24 hours
ASPIRIN EXTRA STRENGTH for example Bayer® Extra Strength 500 mg per pill
DOSE &
FREQUENCY
1 or 2 pills every 4 to 6 hours
DAILY LIMIT Do not take more than 8 pills in 24 hours
Aspirin dosage daily limit is 4,000 mg

Get your dose and frequency right to decrease your risk of harmful side effects

With NSAIDs*, the risk of harmful side effects increases if you take more than directed or for longer than directed. All NSAIDs can cause side effects that harm your kidneys and stomach. Non-aspirin NSAIDs, such as ibuprofen or naproxen sodium, increase the risk for heart attack, heart failure, and stroke.

Small dose in short time icon

Take the smallest effective dose, and take it for the shortest amount of time needed. Why?

NSAIDs can cause stomach bleeding, reduced kidney function, and other side effects. The chance of harmful side effects increases the more you take or the longer you take them.

One NSAID at a time icon

Take ONLY 1 medicine that contains an NSAID at a time. Why?

More than 900 OTC and prescription medicines (see examples) contain an NSAID. Taking more than one NSAID at a time can increase your risk of harmful side effects such as stomach bleeding, heart attack, or stroke.

Heart icon

Maintain the benefit of your aspirin heart therapy. How?

If you take aspirin to help protect against heart attack or stroke, be aware that taking ibuprofen may decrease that heart health benefit.

Remember: It is important to always read and follow the label. If you have any questions or are unsure which pain reliever may be right for you, talk with your healthcare professional.

*NSAID = nonsteroidal anti-inflammatory drug